Product Description: CP21R7 is potent GSK-3β inhibitor, with an IC50 of 1.8 nM; CP21R7 also shows inhibitory activitiy against PKCα, with an IC50 of 1900 nM.
Applications: Cancer-Kinase/protease
Formula: C19H15N3O2
References: [1]Gong L, et al. Discovery of potent and bioavailable GSK-3beta inhibitors. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1693-6./[2]Patsch C, et al. Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells. Nat Cell Biol. 2015 Aug;17(8):994-1003.
CAS Number: 125314-13-8
Molecular Weight: 317.34
Compound Purity: 99.63
Research Area: Cancer
Solubility: DMSO : ≥ 32 mg/mL
Target: GSK-3