CPT1A blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89237.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Region Sequence: C-DPAQTVEQRLKLFK

Full Name: carnitine palmitoyltransferase 1A (liver)

• SKU: GTX89237-PEP-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX89237-PEP-100
• Package Unit: 100 μg
• Quantity Unit: STK
• Human Gene ID: 1374