Clone Name: HL2776
Light Chain: Kappa
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 37
Specificity/Sensitivity: Based on the internal tests, this antibody can recognize human CREB phosphorylated at Ser133 and human ATF1 phosphorylated at Ser63 due to sequence homology.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Uniprot ID: P16220
Antigen Species: Human
Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Ser133 of human CREB1. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: cAMP responsive element binding protein 1