CWHM-12, CAS 1564286-55-0

Product Description: CWHM-12 is a potent inhibitor of αV integrins with IC50s of 0.2, 0.8, 1.5, and 1.8 nM for αvβ8, αvβ3, αvβ6, and αvβ1.

Applications: Cancer-programmed cell death

Formula: C26H32BrN5O6

References: [1]Henderson NC, et al. Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med. 2013 Dec;19(12):1617-24./[2]Basta J, Robbins L, Stout L, Prinsen MJ, Griggs DW, Rauchman M. Pharmacologic inhibition of RGD-binding integrins ameliorates fibrosis and improves function following kidney injury. Physiol Rep. 2020;8(7):e14329.

CAS Number: 1564286-55-0

Molecular Weight: 590.47

Compound Purity: 99.94

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Integrin

• SKU: MEXHY-18644-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18644-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK