CXCL14/BRAK, Human

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Product Description: CXCL14 (also known as breast and kidney-expressed chemokine (BRAK)), as a non-ELR CXC chemokine. CXCL14 displays chemotactic activity for monocytes but not for B and T cells. CXCL14 is involved in cancer, immune responses, and epithelial cell proliferation and migration. CXCL14 is a potent inhibitor of angiogenesis, and also shows antimicrobial activity[1][2]. CXCL14/BRAK Protein, Human is produced in E. coli, and consists of 77 amino acids (S35-E111).

Formula: 9547(Gene_ID)O95715 (S35-E111)(Accession)

References: [1]Arezoo Gowhari Shabgah, et al. Chemokine CXCL14; a double-edged sword in cancer development. Int Immunopharmacol. 2021 Aug;97:107681./[2]Joseph A Westrich, et al. The multifarious roles of the chemokine CXCL14 in cancer progression and immune responses. Mol Carcinog. 2020 Jul;59(7):794-806./[3]Galina V Shurin, et al. Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by dendritic cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo. J Immunol. 2005 May 1;174(9):5490-8.

Molecular Weight: Approximately 13-15 kDa

Compound Purity: 98.0

• SKU: MEXHY-P72683-10UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P72683-10UG
• Package Unit: 10 μg
• Quantity Unit: STK