Clone Name: H342
Light Chain: Kappa
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Positive Control: Appendix: A strong CXCR7 staining should be seen in lymphocytes and epithelial cells.
Negative Control: Appendix: Smooth muscle cells must be negative.
Specificity/Sensitivity: <b>Highly recommended for IHC-P in human tissues.</b>
Form: Liquid
Buffer (with preservative): PBS, 2% BSA, 20% Glycerol, 0.025% ProClin 300.
Concentration: 0.08 mg/ml
Background: This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]
Uniprot ID: P25106
Antigen Species: Human
Immunogen: Synthetic peptide encompassing a sequence within the Intracellular domain of human CXCR7. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: atypical chemokine receptor 3