Cyclosporin A, CAS 59865-13-3

Shelf life (days): 1460.0

Formulation: A solid

Purity: ≥99%

Formula Markup: C62H111N11O12

Formula Weight: 1202.6

CAS Number: 59865-13-3

Notes: Cyclosporin A is an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells (IC50 = 5 nM).{24989,20555,25125} It blocks the transcription of genes involved in T cell activation by interfering with the calcineurin-driven nuclear import of the transcription factor NFAT.{24989,21639,21213} Because of its powerful immunosuppressant activity, cyclosporin A has long been used for the prevention of transplant rejection.{25124}

• SKU: CAY12088-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 12088-100
• Package Unit: 100 mg
• Quantity Unit: STK