Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N,N-dicyclohexyl-5-cyclopropyl-3-isoxazolecarboxamide
Purity: ≥98%
Formula Markup: C19H28N2O2
Formula Weight: 316.4
CAS Number: 945128-26-7
Notes: The sphingosine 1-phosphate (S1P) receptor S1P3 has roles in vasodilation, epithelial barrier function, cardioprotection, fibrosis, immunity, and inflammation.{16449,24542} CYM 5541 is a selective, allosteric agonist of S1P3 (EC50 = 72-132 nM).{24544,24543} It less effectively activates S1P1 (EC50 = 28-38 µM) and is ineffective at S1P2, S1P4, and S1P5 as well as a panel of other receptors, ion channels and transporters.{24544}