Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 3-hydroxy-D-tyrosine
Purity: ≥95%
Formula Markup: C9H11NO4
Formula Weight: 197.2
CAS Number: 5796-17-8
Notes: D-DOPA is an enantiomer of the dopamine precursor L-DOPA (Item No. 13248). It can be converted to L-DOPA via sequential oxidation and transamination, which are mediated by D-amino acid oxidase (DAAO) and DOPA transaminase, respectively, in rat kidney homogenates.{57222} It reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner.{57223} Intraventricular administration of D-DOPA (200 µg/animal) increases striatal dopamine levels in rats.{57224} D-DOPA (20 mg/kg, i.p.) induces contralateral turns in a rat model of Parkinson's disease induced by 6-OHDA (Item No. 25330).{57225}