Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N5-[imino(nitroamino)methyl]-D-ornithine, methyl ester, monohydrochloride
Purity: ≥95%
Formula Markup: C7H15N5O4 / HCl
Formula Weight: 269.7
CAS Number: 50912-92-0
Notes: N(G)-Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME; Item No. 80210). D-NAME was initially thought to be inactive and was often used as a negative control for L-NAME.{33894,33892} Later studies showed that D-NAME (40 mg/kg/day in rats) can have similar but less pronounced effects as L-NAME (40 mg/kg/day in rats) in the cardiovascular system, particularly at long-term timepoints.{33891} D-NAME (3-10 µg/mouse) had no effect on nociception in mice assessed using the tail flick test.{33893}
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