D4-abiraterone, CAS 154229-21-7

Product Description: D4-abiraterone is a major metabolite of abiraterone. D4-abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor.

Applications: Cancer-programmed cell death

Formula: C24H29NO

References: [1]Li Z, et al. Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer. Nature. 2015 Jul 16;523(7560):347-51.

CAS Number: 154229-21-7

Molecular Weight: 347.502

Compound Purity: 99.75

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Androgen Receptor;Cytochrome P450

• SKU: MEXHY-109619-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-109619-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK