Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-13C-d3-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-ß-alanine
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C24[13C]H22D3N7O3
Formula Weight: 475.5
CAS Number: 2967480-55-1
Notes: Dabigatran-13C-d3 is intended for use as an internal standard for the quantification of dabigatran (Item No. 17133) by GC- or LC-MS. Dabigatran is an inhibitor of thrombin (Ki = 0.0045 µM) and an active metabolite of the thrombin inhibitor prodrug dabigatran etexilate (Item No. 17131).{28063,28064} It also inhibits trypsin (Ki = 0.0503 µM) but is selective for thrombin and trypsin over plasmin, Factor Xa, activated protein C, and tissue plasminogen activator (tPA; Kis = 1.695, 3.76, 20.93, and 45.36 µM, respectively).{28063}
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