Dabigatran etexilate-d13, CAS 2749293-92-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[[2-[[[4-[[[(hexyl-d13-oxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-ß-alanine, ethyl ester

Purity: ≥99% deuterated forms (d1-d13)

Formula Markup: C34H28D13N7O5

Formula Weight: 640.8

CAS Number: 2749293-92-1

Notes: Dabigatran etexilate-d13 is intended for use as an internal standard for the quantification of dabigatran etexilate (Item Nos. 17131 / 35248) by GC- or LC-MS. Dabigatran etexilate is a prodrug form of the thrombin inhibitor dabigatran (Item No. 17133).{62763} It inhibits thrombin-induced platelet aggregation in isolated rabbit platelets (IC50 = 0.337 µM) and inhibits thrombus formation in a rat model of venous thrombosis (ED50 = 7.8 µmol/kg). Formulations containing dabigatran etexilate have been used to reduce the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation and in the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism.

• SKU: CAY18451-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 18451-500
• Package Unit: 500 µg
• Quantity Unit: STK
• Application: GC-MS, LC-MS, Isotopenmarkierung