Dapivirine, CAS 244767-67-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]-benzonitrile

Purity: ≥98%

Formula Markup: C20H19N5

Formula Weight: 329.4

CAS Number: 244767-67-7

Notes: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of HIV-1 reverse transcriptase. Dapivirine, a diarylpyrimidine derivative of the potent NNRTI efavirenz (Item No. 14412), inhibits HIV-1 reverse transcriptase with an IC50 value of 24 nM in vitro.{29624} It impedes the late stages of HIV-1 infection by interfering with HIV-1 Gag-Pol polyprotein processing.{22818}

• SKU: CAY16247-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 16247-25
• Package Unit: 25 mg
• Quantity Unit: STK