Product Description: Dasabuvir (ABT-333) is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC50 values of 7.7 and 1.8 nM, respectively[1].
Applications: COVID-19-anti-virus
Formula: C26H27N3O5S
References: [1]Kati W, et al. In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor. Antimicrob Agents Chemother. 2015 Mar;59(3):1505-11.
CAS Number: 1132935-63-7
Molecular Weight: 493.57
Compound Purity: 98.70
Research Area: Infection
Solubility: DMSO : ≥ 46 mg/mL
Target: DNA/RNA Synthesis;HCV