dBET1, CAS 1799711-21-9

Description: dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis.

CAS Number: 1799711-21-9

Formula: C38H37ClN8O7S

Molecular Weight: 785,27

References: Winter GE, et al. DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation. Science. 2015 Jun 19;348(6241):1376-81.

• SKU: TGMT4495-1mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T4495-1mg
• Package Unit: 1 mg
• Quantity Unit: STK