Product Description: Delgocitinib (JTE-052) is a specific JAK inhibitor with IC50s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively[1].
Applications: COVID-19-immunoregulation
Formula: C16H18N6O
References: [1]Tanimoto A, et al. Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo. Inflamm Res. 2015 Jan;64(1):41-51.
CAS Number: 1263774-59-9
Molecular Weight: 310.35
Compound Purity: 99.87
Research Area: Inflammation/Immunology
Solubility: DMSO : ≥ 58 mg/mL
Target: JAK