Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 5,6-dihydro-2,3-dihydroxy-9,10-dimethoxy-dibenzo[a,g]quinolizinium
Purity: ≥98%
Formula Markup: C19H18NO4
Formula Weight: 324.356
CAS Number: 25459-91-0
Notes: An isoquinoline alkaloid with diverse biological activities; reduces viability, colony formation, and migration and invasion in A549 and H1299 cells at 40 µM; increases hepatic mitochondrial levels of GSH and Gpx4, reduces hepatic mitochondrial levels of TBARS, decreases hepatic swelling of mitochondria, and increases serum activity of Alt in a mouse model of ethanol-induced oxidative liver damage at 40 mg/kg per day; decreases hepatic levels of iNos and triglycerides in the same model at the same dose; reduces hepatic collagen levels and increases survival in a mouse model of thioacetamide-induced hepatic fibrosis at 10 mg/kg per day
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