Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (2aS,4aS,5R,6S,7R,7aS,7bR)-decahydro-1,7b-dimethyl-6-(1-methylethyl)-7,5-(epoxymethano)-1H-cyclopent[cd]indol-9-one
Purity: ≥95%
Formula Markup: C16H25NO2
Formula Weight: 263.37524
CAS Number: 2115-91-5
Notes: Dendrobine is a sesquiterpenoid that has been found in D. nobile and has anticancer activity.{46864,46865} It decreases viability of A549 cells when used at concentrations ranging from 2.5 to 15 µg/ml.{46865} It induces apoptosis in A549 cells when used at concentrations ranging from 1 to 10 µg/ml, as well as increases JNK phosphorylation and sensitizes A549 cells to cisplatin (Item No. 13119) at 10 µg/ml. Dendrobine (50 mg/kg per day) reduces tumor growth in an A549 mouse xenograft model with an additive effect when used in combination with cisplatin.
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