Denfivontinib (hydrochloride), CAS 1457983-33-3

Product Description: Denfivontinib (G-749) hydrochloride is an AXL inhibitor that has synergistic antitumor effects with the PD-1 inhibitor Pembrolizumab (HY-P9902). Denfivontinib can enhance the NOD-like receptor pathway, thereby promoting the formation of the NLRP3 inflammasome[1].

Formula: C25H26BrClN6O2

References: [1]Kim DK, et al. Denfivontinib activates effector T-cells through NLRP3-inflammasome, yielding potent anticancer effects by combination with pembrolizumab. Mol Cancer Ther. 2024 Dec 5.

CAS Number: 1457983-33-3

Molecular Weight: 557.87

Research Area: cancer

Target: TAM Receptor

• SKU: MEXHY-W400801-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W400801-0
• Package Unit: Get quote
• Quantity Unit: STK