Denifanstat, CAS 1399177-37-7

Product Description: Denifanstat (TVB-2640) is an orally active and potent Fatty Acid Synthase (FASN) inhibitor with an IC50 of 0.052 μM and an EC50 of 0.072 μM. Denifanstat has the potential for fatty liver disease and cancer research[1][2].

Formula: C27H29N5O

References: [1]Johan D., et al. Heterocyclic modulators of lipid synthesis. WO2012122391A1./[2]Minhyoung Lee, et al. Fatty Acid Synthase inhibition prevents palmitoylation of SARS-CoV2 Spike Protein and improves survival of mice infected with murine hepatitis virus. BioRxiv, December 21, 2020.

CAS Number: 1399177-37-7

Molecular Weight: 439.55

Compound Purity: 99.58

Research Area: Cancer; Metabolic Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Fatty Acid Synthase (FASN)

• SKU: MEXHY-112829-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112829-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK