Deruxtecan, CAS 1599440-13-7

Shelf life (days): 1460

Info: A reactive drug-linker molecule containing Dxd; has been linked trastuzumab as an ADC to target Dxd to tumor cells; binds to HER2 in a cell-free assay, is cytotoxic to breast cancer cells in vitro, and induces tumor regression in a BT474 breast cancer mouse xenograft model. when linked to trastuzumab

Formulation: A solid

Formal Name: N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[[2-[[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-1-yl]amino]-2-oxoethoxy]methyl]-glycinamide

Purity: ≥98%

Formula Markup: C52H56FN9O13

Formula Weight: 1034.068403

CAS Number: 1599440-13-7

• SKU: CAY43189-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43189-5
• Package Unit: 5 mg
• Quantity Unit: STK