Product Description: Desethoxy Quetiapine dihydrochloride (Compound 28) is an antagonist for dopamine D2 receptor with an IC50 of 1330 nM. Desethoxy Quetiapine dihydrochloride antagonises Apomorphine (HY-12723)-induced climbing and swimming disruption in mouse models[1].
Formula: C19H23Cl2N3OS
References: [1]Warawa EJ, et al., Behavioral approach to nondyskinetic dopamine antagonists: identification of seroquel. J Med Chem. 2001 Feb 1;44(3):372-89.