Desethylchloroquine-d4, CAS 1189971-72-9

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N4-(7-chloro-4-quinolinyl)-N1-ethyl-1,4-pentane-1,1,2,2-d4-diamine

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C16H18ClD4N3

Formula Weight: 295.84304

CAS Number: 1189971-72-9

Notes: Desethylchloroquine-d4 is intended for use as an internal standard for the quantification of desethylchloroquine (Item No. 30113) by GC- or LC-MS. Desethylchloroquine is a major active metabolite of chloroquine (Item No. 14194).{52376} Desethylchloroquine is formed when chloroquine undergoes dealkylation, primarily by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP3A4 and to a lesser extent by CYP2D6. It inhibits the growth of the P. falciparum strain LA136 in vitro (IC50 = 9.9 ng/ml).{52377}

• SKU: CAY30907
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 30907-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: GC-MS, LC-MS, Isotopenmarkierung