Product Type: Inducer
CAS No.: 50-02-2
MolecularFormula: C22H29FO5
Molecular Weight: 392,47
Source: Synthetic
Purity: >98%
Solubility: Soluble to 100 mM in DMSO
Appearance: White solid
PubChem CID: 5743
Scientific Background: Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs. It is an anti-inflammatory and immunosuppressant. In cancer patients, it can be give to augment the antiemetic effect of 5-HT3 receptor antagonists, and is also used to counteract the development of edema (1). In a diagnostic setting, it is used to suppress the natural pituitary-adrenal axis (2).
References: 1. Roila F., and Fatigoni S. (2006) Ann Oncol.17 (Suppl2): ii96-ii100.2. Hasan E.A., Jessop D.S., Power L.L. Monk P.T. and Kirwan J.R. (2009) Int J Endocrinol. 2009: 391284.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.