DG-172 (hydrochloride), CAS 1361504-77-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-bromo-aZ-[[4-(4-methyl-1-piperazinyl)phenyl]methylene]-benzeneacetonitrile, dihydrochloride

Purity: ≥98%

Formula Markup: C20H20BrN3 / 2HCl

Formula Weight: 455.2

CAS Number: 1361504-77-9

Notes: DG-172 is an orally available inverse agonist of PPARβ/δ (IC50 = 27 nM), down-regulating transcription of ANGPTL4 in mouse myoblasts (IC50 = 9.5 nM).{31239} It alters the differentiation of bone marrow cells, augmenting GM-CSF-induced development into subsets of mature and immature dendritic cells.{31238} Inverse agonists of PPARβ/δ, including DG-172, inhibit cancer cell invasion through suppression of ANGPTL4 expression.{31237}

• SKU: CAY19128-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19128-10
• Package Unit: 10 mg
• Quantity Unit: STK