DIF-3, CAS 113411-17-9

Product Description: DIF-3 reduces the expression levels of cyclin D1 and c-Myc by facilitating their degradation via activation of GSK-3β. DIF-3 inhibits Wnt/β-catenin signaling pathway-related proteins in DLD-1 cells. DIF-3 exerts a strong antiproliferative effect on the human cervical cancer cell line HeLa by inducing cyclin D1 degradation and inhibiting cyclin D1 mRNA expression[1].

Applications: Cancer-Kinase/protease

Formula: C13H17ClO4

References: [1]Naoya Kubokura , et al. Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo. J Pharmacol Sci. 2015 Apr;127(4):446-55.

CAS Number: 113411-17-9

Molecular Weight: 272.72

Compound Purity: 98.07

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: CDK;GSK-3

• SKU: MEXHY-145669-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-145669-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK