Dihydrochalcone, CAS 1083-30-3

Product Description: Dihydrochalcone (3-Phenylpropiophenone) is a BBB-penatrable Aβ aggregation inhibitor. Dihydrochalcone destabilizes Aβ17-42 protofibrils by disrupting the β-sheet of β1 region. Dihydrochalcone destabilizes both U-shaped Aβ40/Aβ42 protofibrils and S-shaped Aβ42 protofibrils by binding to the protofibril cavity. Dihydrochalcone is the main component of daemonorops draco tree[1].

Formula: C15H14O

References: [1]Jin Y, et al. Dihydrochalcone molecules destabilize Alzheimer's amyloid-β protofibrils through binding to the protofibril cavity. Phys Chem Chem Phys. 2018 Jun 27;20(25):17208-17217.

CAS Number: 1083-30-3

Molecular Weight: 210.27

Compound Purity: 99.87

Research Area: Neurological Disease

Target: Amyloid-β

• SKU: MEXHY-114508-1G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-114508-1G
• Package Unit: 1 g
• Quantity Unit: STK