Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 1,7-bis(3,4-dimethoxyphenyl)-1,6-heptadiene-3,5-dione
Purity: ≥90%
Formula Markup: C23H24O6
Formula Weight: 396.4
CAS Number: 160096-59-3
Notes: Dimethoxycurcumin is a derivative of curcumin (Item No. 81025) that has anti-inflammatory and antioxidant activities.{53899,53900,53901} It inhibits mitogen-induced proliferation of CD4+ T cells, CD8+ T cells, and B cells, as well as secretion of IL-2, IL-4, IL-6, and IFN-γ induced by concanavalin A (Item No. 14951) in isolated human lymphocytes when used at concentrations ranging from 1 to 10 µM.{53899} Dimethoxycurcumin (1-10 µM) inhibits LPS-induced nitric oxide (NO) production and expression of inducible nitric oxide synthase (iNOS) in RAW 264.7 cells.{53900} It inhibits hemolysis of isolated human red blood cells (RBCs) induced by AAPH (Item No. 82235) when used at a concentration of 10 µM.{53901}