Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 4-(1,2-dihydroxyethyl)-1,2-benzenediol
Purity: ≥90%
Formula Markup: C8H10O4
Formula Weight: 170.6
CAS Number: 28822-73-3
Notes: DL-3,4-Dihydroxyphenyl glycol is an active metabolite of the endogenous neurotransmitter norepinephrine (Item No. 35580).{68188} It is produced by the deamination of norepinephrine by monoamine oxidase (MAO) in the cytosol.{68189} DL-3,4-Dihydroxyphenyl glycol scavenges DPPH (Item No. 14805) radicals in a cell-free assay (IC50 = 1.55 µM).{68187} It reduces LPS-induced nitrite production in isolated mouse peritoneal macrophages when used at concentrations of 50 and 100 µM. DL-3,4-Dihydroxyphenyl glycol (50 and 100 µM) decreases increases in inducible nitric oxide synthase (iNOS) and COX-2 levels induced by LPS in isolated mouse macrophages. It also inhibits LPS-induced degradation of IκBα in isolated mouse macrophages.
English
Deutsch
