DL-Propargyl Glycine (hydrochloride), CAS 16900-57-5

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-amino-4-pentynoic acid, monohydrochloride

Purity: ≥95%

Formula Markup: C5H7NO2 / HCl

Formula Weight: 149.6

CAS Number: 16900-57-5

Notes: Hydrogen sulphide (H2S), a naturally occurring gasotransmitter, is a potent vasodilator and pro-inflammatory mediator.{15636} DL-Propargyl glycine (PAG) is an irreversible inhibitor of the H2S synthesizing enzyme cystathionine-γ-lyase (CSE). PAG blocks H2S synthesis activity in rat liver preparations with an IC50 value of 55 µM and abolishes the rise in plasma H2S in anaesthetized rats induced with hemorrhagic shock.{16094} At concentrations ranging from 25-100 mg/kg, PAG can reduce H2S-associated inflammation in rodent models of pancreatitis, oedema, and endotoxemia.{16095,16096,16097}

• SKU: CAY10010948-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10010948-10
• Package Unit: 10 mg
• Quantity Unit: STK