Product Description: DMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C26H18F2N2O
References: [1]Ipavec V, et al. KV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus. Pharmacol Res. 2011 Oct;64(4):397-409./[2]Zaczek R, et al. Two new potent neurotransmitter release enhancers, 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone and 10,10-bis(2-fluoro-4-pyridinylmethyl)-9(10H)-anthracenone: comparison to linopirdine. J Pharmacol Exp Ther. 1998 May;285(2):724-30.
CAS Number: 160588-45-4
Molecular Weight: 412.43
Compound Purity: 99.96
Research Area: Neurological Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Potassium Channel