M3541, CAS 1360628-91-6

Product Description: M3541 is a potent, ATP-competitive and selective ATM inhibitor with an IC50 of 0.25 nM. M3541 shows remarkable selectivity against other protein kinases. M3541 suppresses double-strand breaks (DSB) repair and has antitumor activities[1].

Applications: Cancer-Kinase/protease

Formula: C23H17FN6O2

References: [1]Astrid Zimmermann, et al. A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies. Mol Cancer Ther. 2022 Jun 1;21(6):859-870.

CAS Number: 1360628-91-6

Molecular Weight: 428.42

Compound Purity: 99.10

Research Area: Cancer

Solubility: DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)

Target: ATM/ATR

• SKU: MEXHY-160096-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160096-5
• Package Unit: 5 mg
• Quantity Unit: STK