Shelf life (days): 730.0
Formulation: A solid
Formal Name: 1,4-dihydro-6,7-dinitro-2,3-quinoxalinedione
Purity: ≥95%
Formula Markup: C8H4N4O6
Formula Weight: 252.1
CAS Number: 2379-57-9
Notes: DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively versus IC50 = 40 μM for NMDA receptors).{23070,23071,23072} This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.{23069}