Dopal, CAS 5707-55-1

Product Description: Dopal is an aldehyde that can be generated in Parkinson's disease by enzymatic degradation of dopamine. Dopal can generate reactive oxygen species (ROS), and triggers aggregation of α-synuclein. Dopal elicits α-synuclein accumulation and hampers α-synuclein clearance in primary neurons[1][2].

Applications: Neuroscience-Neurodegeneration

Formula: C8H8O3

References: [1]Masato A, et al. DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson's disease. NPJ Parkinsons Dis. 2023 Mar 25;9(1):42. /[2]Bloch DN, et al. Scavenging neurotoxic aldehydes using lysine carbon dots. Nanoscale Adv. 2023 Jan 19;5(5):1356-1367.

CAS Number: 5707-55-1

Molecular Weight: 152.15

Compound Purity: 77.0

Research Area: Neurological Disease

Target: α-synuclein

• SKU: MEXHY-121252-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-121252-10
• Package Unit: 10 mg (65.72 mM * 1 mL in Methanol)
• Quantity Unit: STK