Doxorubicinone-13C,d3

Product Description: Doxorubicinone-13C,d3 (Adriamycin aglycone-13C,d3) is 13C labeled Doxorubicinone. Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.

Applications: Cancer-programmed cell death

Formula: C20 13CH15D3O9

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]M Joerger, et al. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma. Cancer Chemother Pharmacol. 2005 May;55(5):488-96.

Molecular Weight: 418.37

Research Area: Cancer

Target: Endogenous Metabolite;Isotope-Labeled Compounds

• SKU: MEXHY-121309S1-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-121309S1-0
• Package Unit: Get quote
• Quantity Unit: STK