DS-7423, CAS 1222104-37-1

Product Description: DS-7423 is a dual PI3K and mTOR inhibitor, with IC50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR, respectively. DS-7423 possesses anti-tumor activity[1][2].

Applications: Cancer-Kinase/protease

Formula: C22H27F3N10O2

References: [1]Katsutoshi Oda, et al. Characterization of TP53 and PI3K signaling pathways as molecular targets in gynecologic malignancies. J Obstet Gynaecol Res. 2016 Jul;42(7):757-62./[2]Tomoko Kashiyama, et al. Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423. PLoS One. 2014 Feb 4;9(2):e87220.

CAS Number: 1222104-37-1

Molecular Weight: 520.51

Compound Purity: 99.75

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: mTOR;PI3K

• SKU: MEXHY-124036-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-124036-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK