Shelf life (days): 1460.0
Formulation: A solid
Formal Name: glycylglycyl-L-leucine
Purity: ≥95%
Formula Markup: C10H19N3O4
Formula Weight: 245.3
CAS Number: 14857-82-0
Notes: DT-109 is a tripeptide.{69878} It reduces blood glucose levels in an oral glucose tolerance test (OGTT) in mice. DT-109 (1 mg/g per day) reduces non-fasting blood glucose levels, serum total cholesterol and LDL levels, and adipocyte hypertrophy in Apo-/- mice. It reduces body fat mass, adipocyte hypertrophy, and hepatomegaly in a mouse model of diet-induced non-alcoholic steatohepatitis (NASH). DT-109 (500 mg/kg per day) also reverses hepatic steatosis and prevents the progression of fibrosis in a cynomolgus monkey model of NASH induced by a high-fat, high-fructose, and high-cholesterol diet.{69879}