(±)-Dunnione, CAS 521-49-3

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2,3-dihydro-2,3,3-trimethyl-naphtho[1,2-b]furan-4,5-dione

Purity: ≥98%

Formula Markup: C15H14O3

Formula Weight: 242.3

CAS Number: 521-49-3

Notes: (±)-Dunnione is a naturally occurring naphthoquinone with diverse biological activities.{40460,40463,40461,40462} (±)-Dunnione also reduces the growth of T. cruzi epimastigotes (IC50 = 4.01 μM).{40463} It is a substrate for NAD(P)H:quinone oxidoreductase 1 (NQO1) that increases production of reactive oxygen species (ROS) and induces cell death of A549 lung carcinoma cells (IC50 = 6.1 μM).{40461} (±)-Dunnione (20 mg/kg per day for 4 days) increases intracellular NAD+ (Item No. 16077) and prevents inflammatory cytokine production and small intestinal damage induced by cisplatin (Item No. 13119) in mice.{40462}

• SKU: CAY21943-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21943-25
• Package Unit: 25 mg
• Quantity Unit: STK