Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (9ß,10a)-pregna-4,6-diene-3,20-dione
Purity: ≥98%
Formula Markup: C21H28O2
Formula Weight: 312.5
CAS Number: 152-62-5
Notes: Dydrogesterone is a synthetic progestogen that has no estrogenic, androgenic, glucocorticoid, or anabolic effects, although it is an agonist of progesterone receptors (EC50 = 12.3 nM) and an antagonist of androgen, mineralocorticoid, and glucocorticoid receptors (IC50s = 28.6, 82.7, and 363 nM, respectively).{46018,46019} Dydrogesterone protects against sound stress-induced abortion in mice when administered at a dose of 1.25 mg per animal prior to the stressor on day five of pregnancy.{46020} Formulations containing dydrogesterone have been used in hormone replacement therapy, in the treatment of menstrual disorders, and to prevent miscarriage.
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