Dynasore, CAS 304448-55-3

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 3-hydroxy-2-[(3,4-dihydroxyphenyl)methylene]hydrazide-2-naphthalenecarboxylic acid

Purity: ≥95%

Formula Markup: C18H14N2O4

Formula Weight: 322.3

CAS Number: 304448-55-3

Notes: Dynasore is a cell-permeable, reversible inhibitor of dynamin 1, dynamin 2, and mitochondrial dynamin, Drp1 GTPase activity (IC50 = 15 μM).{22175}{22174} Through this action, dynasore inhibits clathrin-dependent vesicle formation and endocytosis, which is necessary for internalization of certain parasites and viruses, as well as particles and receptor ligands.{22171}{22170}{22172} In some cases, dynasore can also augment the release of neurotransmitters and secreted cytokines.{22173}{22176}

• SKU: CAY14062-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 14062-5
• Package Unit: 5 mg
• Quantity Unit: STK