Product Description: (E/Z)-NSAH is an isoform of NSAH (HY-114503), which is reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively[1].
Applications: Cancer-programmed cell death
Formula: C18H14N2O3
References: [1]Md Faiz Ahmad, et al. Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8241-8246.
CAS Number: 54009-54-0
Molecular Weight: 306.32
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: DNA/RNA Synthesis