E4177, CAS 135070-05-2

Product Description: E4177 (57G709) is an orally active angiotensin II receptor antagonist. E4177 can inhibit the growth of vascular smooth muscle cells (HASMC) and the increase of cell surface area. In addition, E4177 can also increase the expression of platelet-derived growth factor (PDGF) receptor. E4177 can be used in the study of vascular diseases[1].

Formula: C24H21N3O2

References: [1]Kuma S, et al. ANGIOTENSIN II‐INDUCED GROWTH OF VASCULAR SMOOTH MUSCLE CELLS IS ASSOCIATED WITH MODULATION OF CELL SURFACE AREA AND PLATELET‐DERIVED GROWTH FACTOR RECEPTOR EXPRESSION[J]. Clinical and experimental pharmacology and physiology, 2007, 34(3): 153-160.

CAS Number: 135070-05-2

Molecular Weight: 383.44

Research Area: Cardiovascular Disease

Target: Angiotensin Receptor;PDGFR

• SKU: MEXHY-106890-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-106890-1
• Package Unit: 1 mg
• Quantity Unit: STK