Product Description: EAAT2 activator 1 is the potent activator of excitatory amino acid transporter 2 (EAAT2). EAAT2 is the major glutamate transporter and functions to remove glutamate from synapses. EAAT2 activator 1 increases EAAT2 protein levels dose-dependently[1].
Applications: Neuroscience-Neuromodulation
Formula: C16H11ClFN3S
References: [1]Xing X, et al. Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators. Bioorg Med Chem Lett. 2011;21(19):5774-5777.
CAS Number: 892415-28-0
Molecular Weight: 331.80
Compound Purity: 98.91
Research Area: Neurological Disease
Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)