Echinomycin, CAS 512-64-1

Product Description: Echinomycin (Quinomycin A) is potent small-molecule and cell-permeable inhibitor of hypoxia-inducible factor-1 (HIF-1) DNA-binding activity. Echinomycin selectively inhibits the cancer stem cells (CSCs) with an IC50 of 29.4 pM[1][2].

Applications: Cancer-programmed cell death

Formula: C51H64N12O12S2

References: [1]Kong D, et al. Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity. Cancer Res. 2005 Oct 1;65(19):9047-55./[2]Wang Y, et al. Targeting HIF1α eliminates cancer stem cells in hematological malignancies. Cell Stem Cell. 2011 Apr 8;8(4):399-411.

CAS Number: 512-64-1

Molecular Weight: 1101.26

Compound Purity: 98.57

Research Area: Cancer

Solubility: DMSO : 5.3 mg/mL (ultrasonic)

Target: Antibiotic;Bacterial;HIF/HIF Prolyl-Hydroxylase

• SKU: MEXHY-106101-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-106101-10
• Package Unit: 10 mg
• Quantity Unit: STK