EGFR (phospho Tyr974) antibody (HL3480)

Clone Name: HL3480

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Specificity/Sensitivity: The full-length EGFR includes the 24 aa signal peptide that is cleaved during EGFR maturation. The Tyr974 of mature EGFR is equivalent to Tyr998 of uncleaved EGFR.

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

Uniprot ID: P00533

Antigen Species: Human

Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Tyr974 of human EGFR. The exact sequence is proprietary.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: epidermal growth factor receptor

• SKU: GTX641365-S-25
• Manufacturer: GeneTex
• Manufacturer SKU: GTX641365-S-25
• Package Unit: 25 μl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Western Blotting
• Isotype: IgG
• Human Gene ID: 1956
• Host: Rabbit
• Conjugate: Unconjugated