Clone Name: HMV3805
Light Chain: Kappa
Application Note: IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Positive Control: Glioblastoma: NGS-defined positive glioblastoma tissue.
Negative Control: Glioblastoma: NGS-defined negative glioblastoma tissue.
Specificity/Sensitivity: <b>Highly recommended for IHC-P in human tissues.</b>
Form: Liquid
Buffer (with preservative): PBS, 2% BSA, 20% glycerol, 0.025% ProClin 300.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
Uniprot ID: P00533
Antigen Species: Human
Immunogen: Synthetic peptide of human EGFRvIII.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: epidermal growth factor receptor
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