EHT 1610, CAS 1425945-60-3

Description: EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, regulating cell cycle and inducing cell apoptosis.

CAS Number: 1425945-60-3

Formula: C18H14FN5O2S

Molecular Weight: 383,4

References: Chaikuad A, et al. An Unusual Binding Model of the Methyl 9-Anilinothiazolo[5,4-f] quinazoline-2-carbimidates (EHT 1610 and EHT 5372) Confers High Selectivity for Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases. J Med Chem. 2016;59(22):10315-1032

• SKU: TGMT15204-100mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T15204-100mg
• Package Unit: 100 mg
• Quantity Unit: STK