Eliapixant, CAS 1948229-21-7

Product Description: Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].

Applications: COVID-19-immunoregulation

Formula: C22H21F3N4O3S

References: [1]Morice A, et, al. Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study. Eur Respir J. 2021 May 13;2004240./[2]Spinaci A, et, al. P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12:653561.

CAS Number: 1948229-21-7

Molecular Weight: 478.49

Compound Purity: 99.95

Research Area: Inflammation/Immunology

Solubility: DMSO : 33.33 mg/mL (ultrasonic;warming;heat to 60°C)

Target: P2X Receptor

• SKU: MEXHY-109170-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-109170-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK