EML4-ALK kinase inhibitor 1, CAS 1373409-08-5

Product Description: EML4-ALK kinase inhibitor 1 is a potent orally active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM[1].

Applications: Cancer-Kinase/protease

Formula: C31H48N8O3

References: [1]Iikubo K, et al. Synthesis and structure-activity relationships of pyrazine-2-carboxamide derivatives as novel echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) inhibitors. Bioorg Med Chem. 2019 Apr 15;27(8):1683-1692.

CAS Number: 1373409-08-5

Molecular Weight: 580.76

Compound Purity: 98.02

Research Area: Cancer

Solubility: DMSO : 110 mg/mL (ultrasonic)

Target: Anaplastic lymphoma kinase (ALK)

• SKU: MEXHY-111752-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-111752-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK